Endocrine Abstracts

In males, peak bone mass as evaluated by DXA is reached at the age of 20–22 years and may be important for the risk of fracture later in life. DXA, however, only provides two-dimensional images and does not allow assessment of bone structure.We used HR-pQCT to assess trabecular and cortical volumetric BMD (vBMD) and bone microarchitecture at the distal radius and tibia in a population based study including healthy male volunteers. Moreover, bone str...

Background: High levels of mannose-binding lectin (MBL), an activator of complement, have been associated with increased mortality and risk of albuminuria in patients with type 2 diabetes. It is not known if MBL is synthesized in human adipose tissue and the effects of weight loss and changes in insulin sensitivity on MBL levels have been poorly elucidated.Methods: Of 36 nondiabetic obese subjects received a very low-calorie diet (VLCD) of 800 kcal/day f...

Aim: Patients with type 2 diabetes (T2DM) have increased risk of cardiovascular disease (CVD) including stroke. The risk of CVD is traditionally assessed using office blood pressure (BP) and lipid profile. Increased arterial stiffness predicts cardiovascular events in the general population. We investigated if arterial stiffness was associated with cerebrovascular disease in patients with T2DM and sex- and age-matched controls indepentl y of classical risk factors.<p class...